Multigeneration Reproduction and Male Developmental Toxicity Studies on Atrazine in Rats

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چکیده

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Multigeneration Reproduction and Male Developmental Toxicity Studies on Atrazine in Rats

BACKGROUND Reproductive toxicity of Atrazine (ATR) was evaluated in two rat multigenerational studies. Development of male reproductive parameters was evaluated in separate studies after prenatal or postnatal exposure. METHODS In multigenerational studies, rats received dietary concentrations of 0, 10, 50, 100 or 500 ppm ATR. In separate studies in female rats, ATR was administered by gavage ...

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Developmental Toxicity Studies with Atrazine and its Major Metabolites in Rats and Rabbits

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Background: According to several reports there is a positive correlation between the lowered quality of semen and any exposure to toxic compound specially those particularly disrupt endocrine functions. Like other herbicides atrazine (ATR) induces endocrine disruption and consequently interferes with sexual hormones physiological functions. Therefore current study was designed in order to evalu...

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ژورنال

عنوان ژورنال: Birth Defects Research Part B: Developmental and Reproductive Toxicology

سال: 2014

ISSN: 1542-9733,1542-9741

DOI: 10.1002/bdrb.21106